Patrick G Kehoe Selected Research

Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)

11/2020	Small RNA modifications in Alzheimer's disease.
1/2017	Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia.
1/2016	A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol.
6/2015	Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia.
5/2014	Pathophysiology of white matter perfusion in Alzheimer's disease and vascular dementia.
7/2012	Assessment of activation of the plasma kallikrein-kinin system in frontal and temporal cortex in Alzheimer's disease and vascular dementia.
1/2011	Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias.
12/2010	Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia.
10/2010	Plasminogen and plasmin in Alzheimer's disease.
7/2009	Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta.

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Patrick G Kehoe Research Topics

Disease

81	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 04/2003
17	Dementia (Dementias) 11/2020 - 04/2007
13	Hypertension (High Blood Pressure) 01/2021 - 04/2007
10	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 11/2020 - 07/2009
9	Cognitive Dysfunction 11/2020 - 06/2003
6	Inflammation (Inflammations) 01/2021 - 11/2010
5	Neuroblastoma 01/2013 - 07/2009
4	Necrosis 01/2011 - 10/2003
3	Atrophy 01/2019 - 01/2012
3	Disease Progression 01/2018 - 01/2009
3	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2013 - 03/2010
3	Amyloid Plaque 03/2010 - 06/2005
2	Pathologic Processes 11/2020 - 05/2014
2	Neuroinflammatory Diseases 01/2013 - 11/2006
2	Rupture 01/2013 - 09/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2012 - 08/2010
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Hyperhomocysteinemia 01/2021
1	Thrombosis (Thrombus) 12/2020
1	Lewy Body Disease (Lewy Body Dementia) 12/2020
1	COVID-19 12/2020
1	Myocardial Ischemia (Ischemic Heart Diseases) 11/2017
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Epilepsy (Aura) 01/2017
1	Shoulder Impingement Syndrome 09/2016
1	Cerebral Small Vessel Diseases 01/2015

Drug/Important Bio-Agent (IBA)

22	Amyloid (Amyloid Fibrils)IBA 12/2020 - 01/2010
16	Antihypertensive Agents (Antihypertensives)IBA 11/2020 - 04/2007
16	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2006
13	Apolipoproteins E (ApoE)IBA 01/2022 - 04/2003
11	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 12/2020 - 08/2005
11	Amyloid beta-PeptidesIBA 11/2018 - 01/2004
7	AngiotensinsIBA 12/2020 - 07/2009
7	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 12/2020 - 04/2007
6	EnzymesIBA 01/2016 - 04/2008
6	CytokinesIBA 01/2012 - 10/2003
4	Angiotensin Receptor AntagonistsIBA 12/2020 - 08/2010
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2012
4	Peptides (Polypeptides)IBA 11/2018 - 07/2009
4	Messenger RNA (mRNA)IBA 01/2012 - 07/2009
3	LipidsIBA 01/2021 - 01/2019
3	Endothelin-1 (Endothelin 1)IBA 11/2018 - 01/2012
3	Neprilysin (Neutral Endopeptidase)IBA 01/2016 - 01/2012
3	Insulysin (Insulin-Degrading Enzyme)IBA 01/2016 - 06/2005
3	Interleukin-10 (Interleukin 10)IBA 02/2014 - 11/2006
3	IronIBA 01/2014 - 01/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2009 - 10/2003
2	PolyaminesIBA 01/2020 - 01/2015
2	SaltsIBA 01/2020 - 11/2018
2	Glutamic Acid (Glutamate)FDA Link 01/2017 - 01/2013
2	Calcium Channels (Calcium Channel)IBA 01/2016 - 01/2012
2	Insulin (Novolin)FDA Link 01/2014 - 04/2012
2	ZincIBA 01/2014 - 01/2010
2	CopperIBA 01/2014 - 01/2010
2	Cholinergic Agents (Cholinergics)IBA 01/2013 - 07/2009
2	Peptide Hydrolases (Proteases)FDA Link 07/2012 - 12/2010
2	PlasminogenIBA 04/2012 - 10/2010
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 04/2012 - 01/2012
2	Biological ProductsIBA 06/2007 - 03/2004
2	ApolipoproteinsIBA 08/2005 - 06/2003
1	Estrogens (Estrogen)FDA Link 01/2021
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2021
1	Glycerol (Glycerine)FDA LinkGeneric 01/2021
1	SphingolipidsIBA 01/2021
1	SynucleinsIBA 12/2020
1	Vasodilator Agents (Vasodilators)IBA 11/2020
1	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2020
1	RNA (Ribonucleic Acid)IBA 11/2020
1	Small Untranslated RNAIBA 11/2020
1	DiureticsIBA 01/2020
1	SodiumIBA 01/2020
1	ZD4054IBA 01/2020
1	Endothelin A ReceptorIBA 01/2020
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	Vasoconstrictor AgentsIBA 11/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2018
1	N-Methylaspartate (NMDA)IBA 01/2018
1	AcetylcholinesteraseIBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Galantamine (Galanthamine)FDA LinkGeneric 01/2018
1	Donepezil (Aricept)FDA LinkGeneric 01/2018
1	Memantine (Namenda)FDA Link 01/2018
1	Losartan (Cozaar)FDA LinkGeneric 01/2018
1	Rivastigmine (Exelon)FDA LinkGeneric 01/2018
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2018
1	Bile Acids and Salts (Bile Acids)IBA 06/2017
1	Transaminases (Aminotransferases)IBA 01/2017
1	Amlodipine (Norvasc)FDA LinkGeneric 01/2016
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2016
1	Serine (L-Serine)FDA Link 06/2015
1	IonsIBA 01/2015
1	Arginine (L-Arginine)FDA Link 01/2015

Therapy/Procedure

5	Therapeutics 01/2022 - 02/2011
1	Intraventricular Infusions 11/2018
1	Drug Prescriptions 01/2018
1	Extracorporeal Shockwave Therapy 09/2016
1	Activities of Daily Living (ADL) 01/2016